Colorado vs. Cincinnati, Picks and Prediction, Wednesday, January 14, 2026

Colorado (12-4, 2-1 Big 12) will be going for their second consecutive road win when they visit Fifth Third Arena on Wednesday night to face Cincinnati (8-8, 0-3 Big 12) at 7 PM. ET. Read on to find out which team picks up the win in this Buffaloes vs. Bearkats prediction. If you are struggling to pick winners, you've come to the right place. We have the best NCAAB Predictions available. 

The Buffaloes are coming off a 73-71 loss to Texas Tech as 5.5-point underdogs. The Bearkats are coming off a 73-72 loss to UCF as 2.5-point underdogs.

Cincinnati won the lone meeting between the two teams last season, 68-62.

Colorado Trying To Bounce Back From Loss

The Buffaloes had their two-game winning streak snapped by the Red Raiders in their last game, giving them their first conference loss of the season. They will try to bounce back from the loss and pick up their third win in their last four games when they play on Wednesday.

Colorado averages 85.5 points per game. They’ve made 49.1 percent of their field goals and 36.3 percent of their three-pointers.

Isaiah Johnson leads the Buffaloes with 15.9 points and 2.9 rebounds per game. Sebastian Rancik averages 13.9 points and 5.6 rebounds per game, while Barrington Hargress averages 13.6 points and 4.8 assists per game.

Colorado is giving up 77.6 points per game. Opponents have made 45 percent of their field goals and 37 percent of their three-pointers against them.

Injuries: Sebastian Rancik (Undisclosed) and Jalin Holland (Undisclosed) are questionable for this game.

Cincinnati Trying To Snap Three-Game Losing Streak

The Bearkats haven’t played well since the start of conference play, losing their first three games. They will try to snap their losing streak and pick up their second straight win over the Buffaloes when they play on Wednesday.

Cincinnati averages 73.6 points per game. They’ve made 43 percent of their field goals and 31.1 percent of their three-pointers.

Baba Miller leads Cincinnati with 12.7 points and 10.6 rebounds per game. Day Day Thomas averages 12.4 points and 3.9 assists per game, while Moustapha Thiam averages 11.4 points and 6.6 rebounds per game.

Cincinnati is giving up 65.8 points per game. Opponents have made 41 percent of their field goals and 32 percent of their three-pointers against them.

Injuries: Kerr Kriisa (Shoulder) is questionable for this game.

Colorado vs. Cincinnati Picks

Point Spread Pick for Colorado vs. Cincinnati

• Colorado Buffaloes to cover. (4 Units)

The Buffaloes have the edge here because they’re playing well offensively, scoring more than 81 points per game on the road, while making over 50 percent of their shots. They’ve also done a better job at the charity stripe, making over 75 percent of their free throws, while the Bearkats make less than 70 percent of theirs. They rebound the ball well and grab more than eight offensive rebounds per game, which will give them more scoring chances. They also don’t turn the ball over much, and won’t give up many easy-scoring opportunities. The Bearkats have struggled defensively during their slump, and will have a hard time slowing down the hot-shooting Buffaloes. Take Colorado to cover the spread.

Over/Under Picks for Colorado vs. Cincinnati

• Over (4 Units)

The Buffaloes average 85.5 points per game. They play at the 88th-fastest pace in the nation, averaging 73.5 possessions per game, and they’re facing a team that gave up 67.3 points per game in their last three games. The Bearkats average 73.6 points per game. They play at the 112th-fastest pace in the nation, averaging 72.8 possessions per game, and they’re facing a team that is giving up 78.8 points per game on the road. Expect these teams to score enough points to push the score over the total.