DePaul Blue Demons vs Georgetown Hoyas Picks, Prediction, Odds, and Line Movement for Wednesday January 28 2026

By: Kyle Kargel Published 01/28/2026, 09:18 AM ET
DePaul vs Georgetown prediction

DePaul heads to Washington for a midweek Big East clash, and this matchup has all the ingredients bettors look for when breaking down college basketball picks. With a recent head to head meeting already on the books and the spread sitting in a tight range, this game comes down to whether DePaul can finally solve its road issues or if Georgetown can build real momentum at home.

Quick Picks and Prediction

  • Spread Pick: DePaul +3.5
  • Total Pick: Under 140.5
  • Projected Final Score: Georgetown 70, DePaul 68

Odds and Line Movement

Opening Odds

Team Spread Total
DePaul +4.5 139.5
Georgetown -4.5 139.5

Current Odds

Team Spread Total
DePaul +3.5 (-110) Over 140.5 (-110)
Georgetown -3.5 (-110) Under 140.5 (-110)

Line Movement - Spread

Date Time DePaul Georgetown
01/27 06:18 PM +4.5 (-115) -4.5 (-105)
01/28 04:21 AM +3.5 (-110) -3.5 (-110)

Line Movement - Total

Date Time Over Under
01/27 06:18 PM 139.5 (-110) 139.5 (-110)
01/27 07:12 PM 138.5 (-110) 139.5 (-110)
01/28 09:47 PM 140.5 (-110) 140.5 (-110)

Key Matchups and Handicap

These teams met earlier this month, and the result told a clear story. DePaul won 56-50 in a game that slowed to a crawl after halftime. Georgetown struggled to generate clean looks, and once the Hoyas fell behind, the half court offense never recovered.

The biggest question here is location. DePaul has been effective in Big East play overall but has yet to win a true road conference game, which explains why Georgetown is favored despite a worse league record. Oddsmakers are betting that the environment at Capital One Arena matters more than the matchup itself.

Georgetown is coming off an important road win at Providence, a game that snapped a long losing stretch and gave the Hoyas some much needed confidence. When KJ Lewis is aggressive and Georgetown can set its defense, the Hoyas look like a different team. DePaul, meanwhile, still relies on grinding possessions and limiting transition chances, which usually points to lower scoring games.

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.
  • DePaul is 4-5 in Big East play but remains winless on the road in conference games.
  • Georgetown is just 2-7 in Big East play but is coming off a road win at Providence.
  • The last meeting between these teams finished with just 106 total points.
  • Both teams tend to play slower, half court oriented games in conference play.

Key Injuries and Notes for DPU and GTWN

  • DPU: Forward J. Lorenz is questionable with an undisclosed issue.
  • DPU: Guard A. Delaliฤ‡ remains out for the season with a knee injury.
  • GTWN: Guard D. Harris-Smith is questionable due to personal reasons.

ATS and Total Picks

  • DePaul +3.5
  • Under 140.5

Final Score Prediction

This sets up as another tight, physical Big East game where points are earned the hard way. Georgetownโ€™s home edge is real, but DePaulโ€™s style keeps them inside the number.

Georgetown 70, DePaul 68

How to Bet DePaul vs Georgetown

If you are looking to play this matchup, shop around using sportsbook promo codes to find the best number. Different best sportsbooks can vary by a half point, which matters in games lined this tightly.

Bettors who prefer alternative options can also explore social sportsbooks, or take advantage of offers like the bet365 bonus code and the fliff promo code to maximize value before tipoff.

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright ยฉ 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Deposit $10 get a $20 Trading Bonus
Play now 18+ Only. Restrictions and eligibility requirements apply. Not available in all jurisdictions. Trading involves high risk and may result in loss of your entire investment. See polymarket.us/tos for more information. The Polymarket US App serves as an independent software provider and affiliate of Polymarket US and Polymarket Clearing, the CFTC-regulated derivatives exchange and clearing organization.