Northern Illinois vs. Loyola Chicago, Picks and Prediction, Friday, November 21, 2025

By: Bosun Akinpelu Published 11/20/2025, 08:48 PM ET
Huskies vs. Ramblers prediction

Northern Illinois (2-3, 0-0 MAC) will be trying to pick up their first road win of the season when they visit Gentile arena on Friday night to face Loyola Chicago (1-4, 0-0 A-10) at 8 PM. ET. Read on to find out which team picks up the win in this Huskies vs. Ramblers prediction.

If you are struggling to pick winners, you've come to the right place. We have the best NCAAB Predictions available. 

The Huskies are coming off a 70-57 loss to Northern Iowa as 19.5-point underdogs. The Ramblers are coming off an 80-67 loss to Colorado State as 3.5-point underdogs.

Loyola Chicago is 5-2 in seven games against Northern Illinois. The last meeting between the two teams was in 2013.

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.

Northern Illinois Trying To Bounce Back From Loss

The Huskies followed up their win over Benedictine with a loss to Northern Iowa in their last game. They will try to bounce back from the loss and pick up their first road win of the season when they play on Friday.

Northern Illinois averages 81.4 points per game. They’ve made 48.3 percent of their field goals and 41.7 percent of their three-pointers.

Dylan Ducommun leads the Huskies with 12 points and seven assists. Daemar Kelly averages 11.2 points and three rebounds per game, while Jao Ituka averages 11 points and 3.2 rebounds per game.

Northern Illinois is giving up 79.8 points per game. Opponents have made 51 percent of their field goals and 35 percent of their three-pointers.

Loyola Chicago Trying To Snap Four-Game Losing Streak

The Ramblers followed up their season-opening win over Cleveland State with four straight losses. They will try to snap their losing streak and pick up their second win of the season when they play on Friday.

Loyola Chicago averages 71.8 points per game. They’ve made 40.6 percent of their field goals and 34 percent of their three-pointers.

Justin Moore leads the Ramblers with 13.2 points and 5.2 assists per game. Miles Rubin averages 12 points and 5.8 rebounds per game, while Deywilk Tavarez averages 11.2 points per game.

Loyola Chicago is giving up 80 points per game. Opponents have made 44.4 percent of their field goals and 42 percent of their three-pointers against them.

Injuries: Kymany Houinsou (Undisclosed) is questionable for this game.

Northern Illinois vs. Loyola Chicago Picks

Point Spread Pick for Northern Illinois vs. Loyola Chicago

  • Northern Illinois Huskies to cover. (4 Units)

The Huskies have the edge here because they’re playing well offensively, scoring more than 80 points per game while making over 48 percent of their shots. They’ve also done a better job at the charity stripe, making over 72 percent of their free throws in their last three games. They rebound the ball well and grab more than eight rebounds per game, which will give them more scoring chances. They also do a good job of protecting the ball and won’t give the Ramblers a lot of easy-scoring opportunities. The Ramblers aren’t very good defensively, and they’re giving up more than 80 points per game at home, so expect them to have a hard time slowing down the Huskies. Go with Northern Illinois to cover the spread.

Over/Under Pick for Northern Illinois vs. Loyola Chicago

  • Over (4 Units)

Northern Illinois averages 81.4 points per game. They play at the 213th-fastest pace in the nation, averaging 72 possessions per game, and they’re facing a team that is giving up 80.3 points per game at home. The Ramblers average 71.8 points per game. They play at the 303rd-fastest pace in the nation, averaging 69.2 possessions per game, and they’re facing a team that is giving up 85 points per game on the road. Expect these teams to score enough points to push the score over the total. The Huskies and Ramblers played over the total in three of their last five meetings.

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Deposit $10 get a $20 Trading Bonus
Play now 18+ Only. Restrictions and eligibility requirements apply. Not available in all jurisdictions. Trading involves high risk and may result in loss of your entire investment. See polymarket.us/tos for more information. The Polymarket US App serves as an independent software provider and affiliate of Polymarket US and Polymarket Clearing, the CFTC-regulated derivatives exchange and clearing organization.